Clinical Correlation with Hyperinsulinemia in Polycystic Ovary Syndrome (PCOS)

Abstract

Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting women of reproductive age, and hyperinsulinemia is commonly associated with this condition. Hyperinsulinemia in PCOS has been linked to several metabolic disturbances, including insulin resistance, obesity, and an increased risk of type 2 diabetes. The presence of hyperinsulinemia in PCOS can exacerbate symptoms such as irregular menstrual cycles, hirsutism, and infertility. This study aims to explore the clinical correlation of hyperinsulinemia in PCOS and its impact on the clinical presentation of the syndrome. A total of 150 women diagnosed with PCOS were enrolled, and their insulin levels, metabolic parameters, and clinical features such as menstrual irregularities, obesity, and hirsutism were analyzed. The results suggest a strong association between hyperinsulinemia and the severity of clinical symptoms in PCOS. This study emphasizes the importance of addressing hyperinsulinemia as part of managing PCOS to improve overall health outcomes.

Keywords: Polycystic ovary syndrome, hyperinsulinemia, insulin resistance, hirsutism, metabolic disturbances, obesity.