Serofrecquancy of Human Immuno Deficiency virus among Known hepatitis Bvirus infected patients attending Talodihospital, SouthkordofanState, Sudan

Amal Ibrahim Elhag *1, Wafa Ibrahim Elhag**2, Mokhtar Zakaria***3, Hamza Abdallh****4.

Amal Ibrahim Elhag *1, Wafa Ibrahim Elhag**2, Mokhtar Zakaria***3, Hamza Abdallh****4. Amal Ibrahim Elhag *1, Wafa Ibrahim Elhag**2, Mokhtar Zakaria***3, Hamza Abdallh****4. *1 M.Sc Student Microbiology Department, Faculty of Medical Laboratory Sciences, Al Neelain University, Sudan. **2 Associate Professor- Microbiology Department, Faculty of Medical Laboratory Sciences, Al-Neelain University,sudan ***3 Talodi hospital, Laboratory department, South Kordofan State, Sudan. ****4 Ministry of Health, Virology lab, Khartoum, State, Sudan *Corresponding Author: Amal Ibrahim Elhag M.Sc Student Microbiology Department, Faculty of Medical Laboratory Sciences, Al Neelain University, Sudan.

Abstract

Background: Co infection with human immuno deficiency virus (HIV) and hepatitis B virus (HBV) is common; worldwide, an estimated 10% of HIV-infected persons have chronic hepatitis B; because The incidence of traditional acquired immunodeficiency syndrome Related opportunistic infections has decreased with successful anti-HIV therapy, liver disease has emerged as a leading cause of morbidity and mortality in HIV-infected individuals. This study aimed to detect serofrecquancy of Human Immuno Deficiency virus among known hepatitis B virus infected patients who attending Talodi hospital, South kordofan State, Sudan. Methods: This was descriptive cross sectional study included HBV infected patients aged between (11-54) years old with mean 30.4 years old conducted in Talodi hospital, South Kordofan, State, Sudan , During the period from November 2014 to January 2015 , 90 serum samples were tested by semi quantitative enzyme linked immune sorbent assay (ELISA) for the presence of anti HIV1, 2, 0 antibodies, and the relations between seropositivity and other factors, eg: age , gender, positive family history of blood transfusion, duration of having hepatitis B infection, surgery, blood transfusion, and cupping, were detected. Generated data were analyzed by using SPSS program. Result : Out of the total 90 patients who were HBsAg positive, attending Talodi hospital, South Kordofan, State, Sudan, were included in this study, 63(70%) were males, 27(30%)were females, out of them 29(32.2%), were positive for HIV. From them 21(23.3%) were males and 8(8.9%) were females. the seropositivity of HIV had associated with risk factors of gender, positive family history, cupping, surgery, and dental surgery. This study shown statistically in significant relationship between seropositivity of HIV and the above mentioned risk factors (p>0.05). Conclusion: the seropositivity of HIV among HBsAg is high in Talodi. Further confirmation and mentoring with large scale specimen is recommended. Keywords: Serofrequency Anti-HIV, Talodi Hospital, South Kordofan State, ELISA