IN VIVO  HYPERGLYCEMIC EFFECT OF  FAGONIA CRETICA LINN ETHANOLIC EXTRACTS ON ALBINO RATS

Omer Abbas Mohamad Jahala¹*, Omer Musa Izzeldin2, Rashid Eltayeb Abdalla3

Omer Abbas Mohamad Jahala¹*, Omer Musa Izzeldin2, Rashid Eltayeb Abdalla3 1 Faculty of Medical Laboratory science, Shendi University, Sudan. 2 Faculty of Science and Technology .Omdurman Islamic University, Sudan. 3 Faculty of Medicine and Surgery, SHENDI UNIVERSTY, Sudan. 3 Faculty of Pharmacy, Ahfad University for Women, Sudan.

Abstract

The use of the plants as medicines is an ancient and reliable practice. Fagonia Cretica linn is well known herbal plant used in traditional medicine of Pakistan, India and Far East, it is reputed to obtain a profitable therapeutically, properties and it has been used in treatment of fever, thirst, vomiting, dysentery, asthma, urinary discharges, and liver troubles. Externally applied as a paste on tumors and other swellings of the neck. Reported to possess potent antibacterial properties against pathogenic organisms, also the scientific studies of the plant proved the presence of hematological, neurological, anticancer, and hepato- activity. The present study targeted study of the effect of the plant on blood glucose level, the study revealed a dose dependant effect on blood glucose level by Fagonia cretica linn starting from the dose (300 mg/kg body wt), The ethanolic extract of Fagonia cretica linn in doses of (100, 300 & 600 mg/kg/body weight) has an increasing effect on the fasting blood glucose.

Keywords: Fagonia cretica linn, extraction, hyperglycemia.