NOVEL SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF SCHIFF BASES OF KETOPROFEN HAVING HETEROCYCLIC MOIETY

Authors

  • Harendra K. Sharma1*, Manoj Sharma2, Vinay Thakur3, Gajanan Pandey4 Harendra K. Sharma1*, Manoj Sharma2, Vinay Thakur3, Gajanan Pandey4 1Department of Chemistry, Bethesda Institute of Technology and Sciences, Gwalior (M.P.) India 474006 2Department of Pharmacology, Shri RNS College of Pharmacy, Gormi, Bhind, India 3Department of Chemistry, Mithibai College, Mumbai (Maharastra) India-400056 4Department of Applied Chemistry, Madhav Institute of Technology and Science, Gwalior-474005 (M.P.) India

Abstract

A new series of two Schiff bases of ketoprofen having heterocyclic moiety have been synthesized in present investigation. We have tested the anti-inflammatory activities of the synthesized compounds in vivo by using carrageenan induced edema model, using ketoprofen as standard. The safety of these newly synthesized derivatives is reflected by toxicity studies.

 

Key Words:  Heterocyclic moiety, Schiff bases, Carrageenan, Anti-inflammatory.

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Published

2012-10-30

How to Cite

Vinay Thakur3, Gajanan Pandey4, H. K. S. M. S. (2012). NOVEL SYNTHESIS AND ANTI-INFLAMMATORY ACTIVITY OF SCHIFF BASES OF KETOPROFEN HAVING HETEROCYCLIC MOIETY. Journal of Biomedical and Pharmaceutical Research, 1(2). Retrieved from http://www.jbpr.in/index.php/jbpr/article/view/470

Issue

Vol. 1 No. 2 (2012)

Section

Research Articles

License

Creative Commons LicenseJournal of Biomedical and Pharmaceutical Research by Articles is licensed under a Creative Commons Attribution 4.0 International License.