EVALUATION OF LEARNING AND MEMORY IN RATS THROUGH ELEVATED PLUS MAZE MODEL

  • Manju Gari RIMS, Ranchi, India
  • Manisha Varshney RIMS, Ranchi, India
DOI: https://doi.org/10.32553/jbpr.v9i2.727
Keywords: Elevated Plus Maze, Alzheimer disease, Memory, Transfer Latency

Abstract

The understanding of dementia has evolved over 2500 years, from a vague notion of unavoidable age-related memory loss, to a present understanding of its characteristic clinical and pathologic features. Alzheimer disease (AD) symptoms include decline in cognitive function and it is most common form of dementia. In this pharmacological study two drugs Metformin and Bacopa monnieri have been tested to evaluate their efficacy in treatment of AD using Elevated Plus Maze model by evaluating effect of these drugs on learning and memory in rats. The results shown during experiments are promising by both these drugs in improvement of learning and memory in rats, and therefore could be the potential therapy in treatment of AD as well.

Published
2020-04-01
How to Cite
Manju Gari, & Manisha Varshney. (2020). EVALUATION OF LEARNING AND MEMORY IN RATS THROUGH ELEVATED PLUS MAZE MODEL. Journal of Biomedical and Pharmaceutical Research, 9(2). https://doi.org/10.32553/jbpr.v9i2.727
Issue
Vol. 9 No. 2 (2020)
Section
Research Articles

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