Drug Utilisation Pattern for Diabetic Foot

Abstract

Introduction: Diabetic mellitus is a chronic disorder which is rapidly raising, major public health problem. Having DM are more prone to multifarious complication like diabetic foot ulcer, which is highly susceptible to infection. Prevalence of bacterial flora in foot ulcer of this study population indicate current medical scenario of increased multidrug resistant diabetic foot infection, appropriate selection of antibiotic plays important role in DFU management increasing prevalence of antibiotic resistance is a major factor for morbidity or mortality in DFU.

The main objective of this study was to asses microbial sensitive resistance to antibiotic and also to know the drug utilisation of antibiotics in DFU.

Method: A prospective observational study was carried out in 123 inpatients, after taking written informed consent from those met the study criteria. The study was done from October 2017 to march 2018 in surgery department. Patient case sheet were reviewed and assessed on daily basis. Culture report form and all other relevant data were collected to assess the utilisation of antibiotic, it’s sensitivity and resistant interaction, drug interactions and ADR were assessed by using Micromedex and other resources available in the department

Result: In this study population, about 87(70.3%) patients were male and 36(29.27%) female. Mainly patients of age range 41-50 is 47(38.21%)followed by 51-60 is 33(26.83%)then 61-70 is 23(18.70%).Hospital

Conclusion: Diabetic foot infections are real public health problem and early diagnosis along with appropriate treatments are essential. Different bacterial profiles and antibiotic sensitivity were found in different DFU. Clinician should try to stay updated in antibiotic sensitivity and resistant pattern of common pathogen in their area for better therapeutic outcome and to minimize medication errors.

Keywords: Diabetic foot ulcer, sensitivity, resistant, utilization of antibiotics, therapeutic outcome.