A Comprehensive Review on Liquid Suspension Containing Guar Gum

Abstract

Guar gum, a naturally occurring galactomannan polysaccharide derived from the seeds of Cyamopsis tetragonoloba, has emerged as a highly functional excipient in liquid pharmaceutical suspensions. Its unique capacity to form highly viscous, pseudoplastic solutions at low concentrations makes it an attractive suspending agent, thickener, and stabilizer in oral liquid dosage forms. Growing research interest in natural-based excipients driven by safety concerns over synthetic polymers has elevated the significance of guar gum in formulation science. This review aims to provide a comprehensive overview of the introduction, need for study, key features, mechanism of drug release, applications, limitations, and formulation and evaluation parameters of liquid suspensions containing guar gum. The article is intended to serve as a useful reference for pharmaceutical researchers and formulation scientists working with natural polymers.

Keywords: Guar gum; liquid suspension; natural polymer; galactomannan; suspending agent; drug release; colon-targeted delivery; pseudoplastic; pharmaceutical excipient; controlled release.