A REVIEW ON MANAGEMENT PRINCIPLES AND MEDICATION OF MYOCARDIAL INFARCTION

Abstract

Myocardial infarction is the most common public health issue and a major cause of death including disorders of heart and blood vessels. Among all heart problems, ventricular fibrillation is the major cause that occurs soon after the onset of ischemia. As the patient reaches hospital major aim is to decrease the size of the infarct. The control and management of MI depend on the pathophysiological conditions and the time course of irreversible myocardial injury. The fundamental goals of managing acute MI include: (i) Duration of exposure of myocardium to ischemia should be minimized. (ii) Rapid reperfusion (iii) Preventing recurrent ischemia and re-occlusion. (iv) Managing cardiac arrhythmia and other mechanical complications. Management of MI requires prompt diagnosis and therapy including Fibrinolytic therapy, Antithrombin agents, Antihypertensive, and currently discovered many kinds of drugs including LCZ696 and new FDA- Approved treatment and therapies.