ATHEROSCLEROSIS OF AORTA - AN AUTOPSY STUDY

Abstract

Background and objectives: Atherosclerosis is a complex and common disease contributing to increased mortality and morbidity. The exact global incidence of atherosclerosis is beyond calculation. Autopsy studies can provide information about the impact and course of atherosclerosis. Present study is undertaken to study the spectrum and distribution of atherosclerotic lesions in the aorta and the association of age, sex, diet, socio-economic status, smoking and alcohol consuming habits with atherosclerosis.

Methods: Specimens of aorta up to its bifurcation were obtained from medico legal autopsies. Sections from representative areas were studied for gross and microscopic evidence of atherosclerosis.

Results: Among the 50 cases studied 35 were males and 15 were females. Aortas of 31 males (77.5%) and 9 females (27.27%) showed evidence of atherosclerosis. Males were affected more than females. Age has a dominant influence on atherosclerosis, it increased with age. 40 (80%) cases showed evidence of aortic atherosclerosis. Alcohol consumption and cigarette smoking trends have dominant role in acceleration of atherosclerotic lesions. Abdominal aorta was most commonly involved.

interpretation and conclusion: Autopsy studies play a vital role in unraveling the spectrum and occurrence of atherosclerosis. This study will help radiologists and surgeons to diagnose and treat abdominal vascular pathology.

Atherosclerosis is a complex and multifactorial disease. The incidence of atherosclerosis in developing countries (like India) is same as developed countries.

Keywords: Autopsy, Atherosclerosis, Aortic atherosclerosis, Aorta.