Effect of Ethanolic Extract of Leaf of Piper Betle Linn as Immunomodulatory Agent: A Unique Role of Phytochemicals.

  • 1Biswajit Majumdar*, 2Md. Nazrul Islam 1Professor and HOD, Department of Biochemistry, Gandaki Medical College, Tribhuvan University, Nepal. 2Professor, Department of Physiology, Chitwan Medical College, Tribhuvan University, Nepal.

Abstract

Background: Biochemical and immunological effect of leaf of Piper betle Linn in rat were studied. Objective: To evaluate the immunomodulatory effect of leaf of Piper betle Linn. Methods: Ethanolic EXTRACT OF LEAF OF Piper betle Linn were administered at doses of 150 and 250 mg/kg body weight for 30 days in wistar albino rats. Immunomodulatory changes and biochemical correlations were investigated. Results: Ethanolic extract of leaf of Piper betle I Linn showed increased antibody production in a dose dependent manner. It enhances the production of RBC, WBC and HB. Conclusion: Ethanolic extract of leaf of Piper betle Linn has positive immunomodulatory activities.

Published
2013-02-27
How to Cite
2Md. Nazrul Islam1. M. (2013). Effect of Ethanolic Extract of Leaf of Piper Betle Linn as Immunomodulatory Agent: A Unique Role of Phytochemicals. Journal of Biomedical and Pharmaceutical Research, 2(1). Retrieved from http://www.jbpr.in/index.php/jbpr/article/view/438
Section
Research Articles