Hypolipidemic Activity of Spinacia Oleracea L. in Atherogenic Diet Induced Hyperlipidemic Rats.

  • Ranjan Kumar Giri 1*, Sunil Kumar Kanungo1, Niroj K. Tripathi2 1Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India. 2Department of Zoology, Berhampur University, Berhampur, Ganjam, Odisha, India.

Abstract

Spinacia oleracea (spinach) of family Amaranthaceae is an important plant used traditionally for medicinal purposes. Hyperlipidemia was induced by treated orally with atherogenic diet. In atherogenic diet induced hyperlipidemic model, the rats receiving Spinacia oleracea powder showed significant reduction in total cholesterol, triglycerides, total protein and elevation of high density lipoprotein cholesterol. Spinacia oleracea was found to possess significant hypolipidemic activity. The results also suggest that Spinacia oleracea  powder at 200mg and 400 mg/kg b.wt. concentrations are an excellent lipid-lowering agent.

KEY WORDS: Cholesterol, Spinacia oleracea, Hyperlipidemic, Triglyceride.

Published
2012-08-20
How to Cite
Kanungo1, Niroj K. Tripathi2R. K. G. 1. S. K. (2012). Hypolipidemic Activity of Spinacia Oleracea L. in Atherogenic Diet Induced Hyperlipidemic Rats. Journal of Biomedical and Pharmaceutical Research, 1(1). Retrieved from http://www.jbpr.in/index.php/jbpr/article/view/457
Section
Research Articles