To Compare the Vas Score of Dexmedetomidine and Clonidine as an Adjuvant to Intrathecal Bupivacaine in Patients Undergoing Total Abdominal Hysterectomy

Abstract

Background: Spinal anaesthesia is commonly used in gynaecological surgeries, with Bupivacaine being the most commonly used anaesthetic. Bupivacaine, on the other hand, has a shorter duration of action. This clinical study was conducted to evaluate the behaviour of intrathecal clonidine and dexmedetomidine as an adjuvant to bupivacaine in augmenting block characteristics in patients undergoing gynaecological procedures.

Methods: A prospective randomized single blind study was conducted in the Department of Anesthesia IGMC SHIMLA at Kamla Nehru state hospital.

Results: In Group C, Mean VAS score was 1±0 at 30 mins, 60 mins and 90 mins, however it increased to 2±0 at 120 mins, 150 mins, 180 mins and 210 mins. After 240 mins, VAS started increasing more in group C and at 270 mins mean VAS score significantly increased to 3±0 and then to 3.11±0.32, 3.63±0.49, 3.80±0.41 at 330 mins, 360 mins and 390 mins respectively.  In Group D, Mean VAS score increased from 1± 0 at baseline and 60 mins to 1.04±0.21, 1.98±0.15 2± 0, 2.07±0.25, 2.13±0.34, 2.98±0.15, 3±0, 3.02±0.15, 3.27±0.45 and 3.81±0.39 3.81±0.39 at 90 mins, 120 mins, 150 mins, 180 mins, 210 mins, 240 mins, 270 mins, 300 mins, 330 mins, 360 mins and 390 mins respectively. 

Conclusion: When compared between the groups, mean VAS score was significantly more in Group C at 240 mins, 330 mins and 360 mins(p≤0.021)