Osama Mohammed M.Khair***3, Hajir Mutasum Mohamed salh*1 , Wafa Ibrahim Elhag**2, Khalid Abd Alah Enan, *1 M.Sc Student Microbiology Department of Faculty of Medical Laboratory Sciences, Al Neelain University, Sudan **2 Association Professor- Microbiology Department, Faculty of Medical Laboratory Sciences, Al-Neelain University ***3 Department of Virology, Central laboratory Khartoum, Sudan, Sudan